Shane Nye, age 9, had a severe sore throat that was diagnosed as "strep throat" at a clinic visit. His mother was given a prescription for an antibiotic, which she did not fill because she received notice that her electricity would be cut off if she did not pay her overdue bill immediately.

Shane Nye, age 9, had a severe sore throat that was diagnosed as “strep throat” at a clinic visit. His mother was given a prescription for an antibiotic, which she did not fill because she received notice that her electricity would be cut off if she did not pay her overdue bill immediately. After paying her electric bill, she had no money left. Ten days later, Shane’s urine became smoky brown, and he did not feel well. His ankles were slightly swollen, so his mother took him to a free clinic. Shane’s diagnosis is acute poststreptococcal glomerulonephritis.

1a. Describe the pathophysiology of Shane’s diagnosis.

1b. What impact did his mother not filling the prescription have on the development of the diagnosis?

Describe the most common setting in which acute kidney injury (AKI) occurs. Discuss the short-term and long-term outcomes of AKI.
Differentiate the pathophysiology of cystitis, pyelonephritis, and glomerulonephritis.
Discuss the staging of chronic kidney disease including pathophysiology, clinical presentation and treatment options.
Proteinuria is present in many cases of declining kidney function. Discuss why protein levels are routinely monitored in patients at risk for kidney disease.
Discuss the pathophysiology of end stage renal disease.
Identify and define the common pediatric urinary and renal disorders including clinical presentation and treatment options.

Shane Nye, age 9, had a severe sore throat that was diagnosed as “strep throat” at a clinic visit. His mother was given a prescription for an antibiotic, which she did not fill because she received notice that her electricity would be cut off if she did not pay her overdue bill immediately.